Periosteum mechanobiology and mechanistic insights for regenerative medicine

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Harnessing mechanobiology of human pluripotent stem cells for regenerative medicine.

Recent advances in human pluripotent stem cells (hPSCs) open new doors for therapeutics of motor neuron (MN)-associated neurodegenerative diseases. However, the MN differentiation process is not yet completely understood. In this Viewpoint, we stress the concept of designing synthetic cell culture surfaces with precisely controlled mechanical properties (such as rigidity) to improve the efficie...

متن کامل

Modeling the Mechanobiology of the Periosteum to Predict & Harness its Regenerative Capacity

Fig. 1. Schematic of one stage bone transport procedure (yellow bone, red periosteum). A portion of diaphyseal bone is denuded of periosteum, osteotomized, and transported over an intramedullary nail to the site of the 2.54-cm critical-sized defect, where it is docked to the distal femur. The periosteal sheath is left in situ to surround the new defect site, leading to full infilling of the new...

متن کامل

Cell Mechanobiology in Regenerative Medicine: Lessons from Cancer

The stem cell “niche” refers to the collective set of cell-extrinsic inputs that controls the functions of stem cells in vivo.1,2 The key regulatory mechanisms within the niche include presentation of soluble and immobilized molecules such as growth factors and cytokines, direct interactions with other cells (e.g., stromal cells), and adhesion to the extracellular matrix (ECM). These diverse in...

متن کامل

Nanosized biomaterials for regenerative medicine

This review discusses recent developments in the field of nanosized biomaterials and their use in tissue regeneration approaches. The aim is to provide an overview of the research focused on nanoparticle-based strategies to stimulate regeneration. In particular, nanoparticles improve the regenerative capabilities of biomaterials offering ways to control surface and mechanical properties. Moreov...

متن کامل

Nanosized biomaterials for regenerative medicine

This review discusses recent developments in the field of nanosized biomaterials and their use in tissue regeneration approaches. The aim is to provide an overview of the research focused on nanoparticle-based strategies to stimulate regeneration. In particular, nanoparticles improve the regenerative capabilities of biomaterials offering ways to control surface and mechanical properties. Moreov...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: BoneKEy Reports

سال: 2016

ISSN: 2047-6396

DOI: 10.1038/bonekey.2016.70